Comments on: Inactivity and Metabolic Health IV

By: Doreen

Doreen — Wed, 20 Feb 2013 12:45:29 +0000

Thank you so much for sharing your knowledge. I find it vey interesting!
Do you think physical activity has the same effect on metabolic health with skinny people? I am recovering from pcos and skinny but there’s not much information out there about people like me, or at least I can’t find it. Ususally the condition is linked to women being overweight in which case physical activity can make a huge difference.

By: Go Kaleo

Go Kaleo — Sun, 03 Feb 2013 20:03:33 +0000

Indeed, there are many, what I consider secondary contributors, to IR. Sugar and carbs would probably even fall into the secondary contributor category under my definition. The evidence is pretty overwhelming for inactivity and energy imbalance as primary drivers, however, and in my experience, which is generally borne out by my research, those secondary contributors become harmless when energy balance and physical activity are appropriate.

Thanks for the link!

By: Dale Favier

Dale Favier — Sun, 03 Feb 2013 19:58:54 +0000

Thank you! Nice summary of the study. (Why, oh why, would someone do a study this big and not spring for the cost of a control group? Sigh.)

By: George @ the High Fat Hep C Diet

George @ the High Fat Hep C Diet — Sun, 03 Feb 2013 19:23:35 +0000

There’s also a connection between insulin resistance and micronutrient and EFA deficiencies, or there wouldn’t be detectable effects from chromium, biotin, magnesium and other nutrients required for insulin signalling. The old concept of the empty calorie has a lot to recommend it. Metabolic flexibility implies flexibility, and therefore some redundancy, in signalling, but micronutrient shortage is going to introduce economy instead?
http://ajcn.nutrition.org/content/45/5/877.full.pdf

Toxins, including popular pharmacueticals and heavy metals, are also implicated in IR, I seem to remember.